Role of CCR6 and CXCR3 in Establishment and Maintenance of Latent HIV Infection

HIV integration sites and implications for maintenance of the reservoir

J Symons, PU Cameron, SR Lewin

2018-03-01

Purpose of review To provide an overview of recent research of how HIV integration relates to productive and latent infection and ..

HIV cure research: print and online media reporting in Australia

Jennifer Power, Bianca Fileborn, Gary W Dowsett, Jayne Lucke, Graham Brown, Jeanne Ellard, Sharon R Lewin, Joseph D Tucker, Sean Slavin, Jeremy Sugarman, Sophie Hill

2017-10-01

OBJECTIVES: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media inte..

Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals

KK Koelsch, TA Rasmussen, WJ Hey-Nguyen, C Pearson, Y Xu, M Bailey, KH Marks, SC Sasson, MS Taylor, R Tantau, S Obeid, B Milner, O Morrissey, AN Pinto, K Suzuki, MP Busch, SM Keating, P Kaiser, S Yukl, JK Wong

2017-07-01

Background: Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to significant changes to the HIV reservoir and HIV..

Human immunodeficiency virus persistence and T-cell activation in blood, rectal, and lymph node tissue in human immunodeficiency virus-infected individuals receiving suppressive antiretroviral therapy

G Khoury, R Fromentin, A Solomon, W Hartogensis, M Killian, R Hoh, M Somsouk, PW Hunt, V Girling, E Sinclair, P Bacchetti, JL Anderson, FM Hecht, SG Deeks, PU Cameron, N Chomont, SR Lewin

2017-03-15

Background. Immune activation and inflammation remain elevated in human immunodeficiency virus (HIV)-infected individuals receivin..

HIV integration sites in latently infected cell lines: Evidence of ongoing replication

J Symons, A Chopra, E Malantinkova, W Spiegelaere, S Leary, D Cooper, CO Abana, A Rhodes, SD Rezaei, L Vandekerckhove, S Mallal, SR Lewin, PU Cameron

2017-01-13

Background: Assessing the location and frequency of HIV integration sites in latently infected cells can potentially inform our un..

Polymorphisms in the CD14 and TLR4 genes independently predict CD4 T-cell recovery in HIV-infected individuals on antiretroviral therapy

YK Yong, EM Shankar, A Solomon, T Spelman, CK Fairley, JH Elliott, J Hoy, PU Cameron, A Kamarulzaman, SR Lewin

2016-01-01

Background: Chronic HIV infection leads to marked depletion of CD4⁺ T cells in the gastrointestinal tract and increased..